NATURAL WEAPON AGAINST DENGUE: LARVICIDAL EFFICACY OF PAPAYA (Carica Papaya L.) FRUIT PEEL ETHANOL EXTRACT ON AEDES ALBOPICTUS
Published 2025-07-18
Keywords
- Aedes albopictus, Biolarvicide, Extract papaya peel, Dengue
Copyright (c) 2025 Nidha Luthfiana Fawziah, Nur Mahdi, Andi Zsazsa Rafiatul Muklis, Deni Setiawan (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Dengue or, as it is commonly known, dengue fever, has become a public health problem in the world, not only in Indonesia. Until now, dengue disease is still not well controlled. Dengue fever is caused by Aedes argypi and Aedes albopictus mosquitoes. The purpose of this study was to determine the effectiveness of papaya peel extract (Carica papaya L) against Aedes albopictus mosquito larvae. This study is an experimental study of post test only control group design using 600 Aedes albopictus larvae. This study used papaya peel extract with 6 concentration treatment groups of 0.4 mg/ml, 0.8 mg/ml, 0.12 mg/ml, 0.16 mg/ml, positive control group and negative control group. Observations were made 24 hours after treatment and larval mortality was calculated every 1 hour. The results showed that the average larval mortality at a concentration of 0.4 mg/ml was 6.25%, concentration of 0.8 mg/ml was 8.25%, concentration of 0.12 mg/ml was 10.75%, at a concentration of 0.16 mg/ml was 14.5%, for the positive control was 100%, and for the negative control was 0%. The results of probit analysis of LC90 of papaya peel extract amounted to 48.501 and LT50 at the fastest killing concentration of 0.16 mg/ml was 59.017 hours. Based on the results of the study, it can be concluded that papaya peel extract (Carica papaya L.) can kill Aedes albopictus mosquito larvae.
References
- Fuadzy, H., & Marina, R. (2012). POTENSI DAUN DEWA (GYNURA PSEUDOCHINA [L.] DC.) SEBAGAI LARVASIDA AEDES AEGYPTI (LINN.). ASPIRATOR, 4(1), 7–13.
- Kemenkes, R. (2022). Infodatin: Deteksi Demam Berdarah Dengue (DBD) dan Pengendaliannya di Indonesia Tahun 2023. PUSAT DATA DAN TEKNOLOGI INFORMASI KEMENTERIAN KESEHATAN RI, 1–16.
- Kesumawati Hadi, U., Soviana, S., & Djayanti Gunandini, D. (2012). Aktivitas nokturnal vektor demam berdarah dengue di beberapa daerah di Indonesia. Jurnal Entomologi Indonesia Indonesian Journal of Entomology, 9(1), 1–6. https://doi.org/10.5994/jei.9.1.1
- Kesumawati, U., Fadilla, Z., Hadi, U. K., & Surachmi Setiyaningsih. (2015). Bioekologi vektor demam berdarah dengue (DBD) serta deteksi virus dengue pada Aedes aegypti (Linnaeus) dan Ae. albopictus (Skuse) (Diptera: Culicidae) di kelurahan endemik DBD Bantarjati, Kota Bogor. Maret, 12(1), 31–38. https://doi.org/10.5994/jei.12.1.31
- Mahdi, N., Ridha, M. R., Setiawan, D., Praristiya, M. R. S., Rahayu, N., & Atmaja, B. P. (2022). Bio-efficacy of Mangifera leaf extracts on mortality of Aedes aegypti and inhibition of egg hatching. Veterinary World, 15(7), 1753–1758. https://doi.org/10.14202/vetworld.2022.1753-1758
- Mahfiroh, S., Norfai, & Zuhrupal Hadi. (2023). Analisis Potensi Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) terhadap Kematian Larva Aedes Albopictus di Laboratorium Balai Litbangkes Tanah Bumbu. Jurnal Kesehatan Indonesia (The Indonesia Journal of Health), 3(3), 131–138.
- Maulana, M., Hidayah, N., Fitri Nugraha, D., & Ketut Gunawan Kusuma, I. (2022). UJI EFEKTIVITAS EKSTRAK ETANOL DAUN PEPAYA (Carica papaya Linn) SEBAGAI BIOLARVASIDA Ae. aegypti BIOLARVACIDES. An-Nadaa: Jurnal Kesehatan Masyarakat, 1, 14–21. https://ojs.uniska-bjm.ac.id/index.php/ANN/article/view/6060
- Qatrinida, Norfai, & Kasman. (2021). POTENSI EKSTRAK JAHE MERAH (Zingiber officinale var. rubrum) SEBAGAI LARVASIDA ALAMI Aedes albopictus. Jurnal Kesehatan Masyarakat, 8(2), 106–113. https://ojs.uniska-bjm.ac.id/index.php/ANN/article/view/3485
- Refai, Hermansyah, H., & Adhe Bianggo NauE, D. (2013). UJI EFEKTIFITAS BIOLARVASIDA EKSTRAK DAUN PAPAYA (CARICA PAPAYA L) TERHADAP KEMATIAN LARVA INSTAR III NYAMUK AEDES AEGYPTI. Jurnal Kesehatan, 1, 91–99.
- Santoso, G. A., Adrianto, H., & Darmanto, A. G. (2020). Uji Efektivitas Ekstrak Kulit Citrus nobilis Sebagai Larvasida Larva Ae. albopictus instar III. Jurnal Kedokteran Dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya, 7(1), 33–38. https://doi.org/10.32539/jkk.v7i1.10728
- Setiawan, D., Hadi, S., Shindi P, M. R., Mahdi, N., Rinda, R. P., & Magelang, U. M. (2025). EFFECTIVENESS TEST OF OIL PALM LEAF EXTRACT (Elaeis guineensis Jacq.) AS A MOSQUITO BIOLARVACIDE Aedes aegypti. JFSP: Jurnal Farmasi Sains Dan Praktis, 11(1), 11–17. https://doi.org/10.31603/pharmacy.v%vi%i.10275
- Wulandari, S., Arnentis, & Rahayu, S. (2012). POTENSI GETAH BUAH PEPAYA (Carica papaya L) TERHADAP MORTALITAS LARVA NYAMUK Aedes albopictus. Jurnal Biogenensis, 9(1), 66–76.